Drugs included in the category of Proton Pump Inhibitor (PPI) that circulated in Indonesia, among others: Esomeprazole, Omeprazole, lansoprazole and Pantroprazole, with a working mechanism to reduce or suppress gastric acid secretion by inhibiting the enzyme activity of H / K ATPase (proton pump) in surface of gastric parietal cells at a pH less than [...]