Clopidogrel with trade name Plavix constitute the medicine as barricade of platelet aggregation. It barricade accordance with selective bundling between adenosin diphosphate (ADP) with platelet receptor, and activate subsequent ADP mediated from GP IIb/IIIa, with the result that hamper platelet aggregation .

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Rheumatoid arthritis is a chronic disease on the body joints which is caused by autoimmune process that be signed by painful, rigidity, swelling and restriction of movements and function of some body joints. It usually be suffered by people who old group of 30 – 50 years.

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Epidemiology and clinical data show that carotenoid like astaxanthin can give us protection toward cardiovascular disease included hypertension. This condition related with blood vessel function disorder, contractible and rhythm change of blood vessel its be mediated by relaxant substance (nitrate oxide NO; prostacycline) and constrictor factor (tromboxant; endothelin) in blood. More then, blood flow characteristic [...]

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The clinical picture of viral hepatitis A is extremely variable, ranging from asymptomatic infection without jaundice to fulminating disease. The clinical characteristics of the viral hepatitis A i.e. :

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Fever is the condition which oral body temperature more than 37,4oC. The average normal oral body temperature is 36,7oC (range 36-37,4oC). Fever is the symptom that is most readily recognized as a sign of illness and brings the patients quickly go to doctor.

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